Ecological dynamics of emerging bat virus spillover

Plowright, Raina K., Eby, Peggy, Hudson, Peter J., Smith, Ina L., Westcott, David, Bryden, Wayne L., Middleton, Deborah, Reid, Peter A., McFarlane, Rosemary A., Martin, Gerardo, Tabor, Gary M., Skerratt, Lee F., Anderson, Dale L., Crameri, Gary, Quammen, David, Jordan, David, Freeman, Paul, Wang, Lin-Fa, Epstein, Jonathan H., Marsh, Glenn A., Kung, Nina Y. and McCallum, Hamish (2014) Ecological dynamics of emerging bat virus spillover. Proceedings of the Royal Society B: Biological Sciences, 282 1798: . doi:10.1098/rspb.2014.2124


Author Plowright, Raina K.
Eby, Peggy
Hudson, Peter J.
Smith, Ina L.
Westcott, David
Bryden, Wayne L.
Middleton, Deborah
Reid, Peter A.
McFarlane, Rosemary A.
Martin, Gerardo
Tabor, Gary M.
Skerratt, Lee F.
Anderson, Dale L.
Crameri, Gary
Quammen, David
Jordan, David
Freeman, Paul
Wang, Lin-Fa
Epstein, Jonathan H.
Marsh, Glenn A.
Kung, Nina Y.
McCallum, Hamish
Title Ecological dynamics of emerging bat virus spillover
Journal name Proceedings of the Royal Society B: Biological Sciences   Check publisher's open access policy
ISSN 0962-8452
1471-2954
Publication date 2014-11-12
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1098/rspb.2014.2124
Open Access Status
Volume 282
Issue 1798
Total pages 9
Place of publication London, United Kingdom
Publisher Royal Society of London
Collection year 2015
Language eng
Formatted abstract
Viruses that originate in bats may be the most notorious emerging zoonoses that spill over from wildlife into domestic animals and humans. Understanding how these infections filter through ecological systems to cause disease in humans is of profound importance to public health. Transmission of viruses from bats to humans requires a hierarchy of enabling conditions that connect the distribution of reservoir hosts, viral infection within these hosts, and exposure and susceptibility of recipient hosts. For many emerging bat viruses, spillover also requires viral shedding from bats, and survival of the virus in the environment. Focusing on Hendra virus, but also addressing Nipah virus, Ebola virus, Marburg virus and coronaviruses, we delineate this cross-species spillover dynamic from the within-host processes that drive virus excretion to land-use changes that increase interaction among species. We describe how land-use changes may affect co-occurrence and contact between bats and recipient hosts. Two hypotheses may explain temporal and spatial pulses of virus shedding in bat populations: episodic shedding from persistently infected bats or transient epidemics that occur as virus is transmitted among bat populations. Management of livestock also may affect the probability of exposure and disease. Interventions to decrease the probability of virus spillover can be implemented at multiple levels from targeting the reservoir host to managing recipient host exposure and susceptibility
Keyword Ebola virus
Emerging infectious diseases of bat origin
Hendra virus in flying-foxes
Marburg virus
Nipah virus
Severe acute respiratory syndrome coronavirus
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: School of Agriculture and Food Sciences
Official 2015 Collection
 
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Citation counts: TR Web of Science Citation Count  Cited 45 times in Thomson Reuters Web of Science Article | Citations
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