Vitamin D and atherosclerosis

Menezes, Arthur R., Lamb, Marie C., Lavie, Carl J. and DiNicolantonio, James J. (2014) Vitamin D and atherosclerosis. Current Opinion in Cardiology, 29 6: 571-577. doi:10.1097/HCO.0000000000000108


Author Menezes, Arthur R.
Lamb, Marie C.
Lavie, Carl J.
DiNicolantonio, James J.
Title Vitamin D and atherosclerosis
Journal name Current Opinion in Cardiology   Check publisher's open access policy
ISSN 0268-4705
1531-7080
Publication date 2014-11
Year available 2014
Sub-type Article (original research)
DOI 10.1097/HCO.0000000000000108
Open Access Status
Volume 29
Issue 6
Start page 571
End page 577
Total pages 7
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Collection year 2015
Language eng
Formatted abstract
Purpose of review: To provide an overview of the association between vitamin D deficiency and atherosclerosis.

Recent findings: Vitamin D exerts protective effects on atherosclerosis through multiple mechanisms. It has been shown to protect against endothelial dysfunction, vascular smooth muscle cell proliferation and migration, and modulation of the immune system, as well as the inflammatory response. In addition, vitamin D has been shown to have systemic effects on insulin resistance, dyslipidemia, and hypertension.

Summary: Vitamin D deficiency is widely prevalent in the United States and worldwide. Although deficiency of this fat-soluble vitamin is usually associated with musculoskeletal disorder, it is associated with a wide range of disease processes that include multiple organ systems. Recently, there has been mounting evidence linking vitamin D deficiency to cardiovascular disease and atherosclerosis.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Medicine Publications
 
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