Overview of the current state-of-the-art for bioaccumulation models in marine mammals

Weijs, Liesbeth, Hickie, Brendan E., Blust, Ronny and Covaci, Adrian (2014) Overview of the current state-of-the-art for bioaccumulation models in marine mammals. Toxics, 2 226-246. doi:10.3390/toxics2020226


Author Weijs, Liesbeth
Hickie, Brendan E.
Blust, Ronny
Covaci, Adrian
Title Overview of the current state-of-the-art for bioaccumulation models in marine mammals
Journal name Toxics   Check publisher's open access policy
ISSN 2305-6304
Publication date 2014-05-27
Sub-type Article (original research)
DOI 10.3390/toxics2020226
Open Access Status DOI
Volume 2
Start page 226
End page 246
Total pages 21
Place of publication Basel, Switzerland
Publisher M D P I AG
Collection year 2015
Language eng
Abstract Information regarding the (toxico)kinetics of a chemical in organisms can be integrated in mathematical equations thereby creating bioaccumulation models. Such models can reconstruct previous exposure scenarios, provide a framework for current exposures and predict future situations. As such, they are gaining in popularity for risk assessment purposes. Since marine mammals are protected, the modeling process is different and more difficult to complete than for typical model organisms, such as rodents. This review will therefore discuss the currently available models for marine mammals, address statistical issues and knowledge gaps, highlight future perspectives and provide general do‟s and don‟ts.
Keyword PBPK models
Marine mammals
Exposure
Bioaccumulation
Organic pollutants
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
National Research Centre for Environmental Toxicology Publications
 
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Created: Mon, 03 Nov 2014, 11:26:02 EST by Robyne Anderson on behalf of National Res Centre For Environmental Toxicology