Projections from the paralemniscal nucleus to the spinal cord in the mouse

Liang, Huazheng, Duan, Deyi, Watson, Charles and Paxinos, George (2013) Projections from the paralemniscal nucleus to the spinal cord in the mouse. Brain Structure and Function, 218 5: 1307-1316. doi:10.1007/s00429-012-0459-5


Author Liang, Huazheng
Duan, Deyi
Watson, Charles
Paxinos, George
Title Projections from the paralemniscal nucleus to the spinal cord in the mouse
Journal name Brain Structure and Function   Check publisher's open access policy
ISSN 1863-2653
1863-2661
Publication date 2013-09
Sub-type Article (original research)
DOI 10.1007/s00429-012-0459-5
Open Access Status
Volume 218
Issue 5
Start page 1307
End page 1316
Total pages 10
Place of publication Heidelberg, Germany
Publisher Springer
Subject 2702 Anatomy
2722 Histology
2800 Neuroscience
Abstract The present study investigated the projection from the paralemniscal nucleus (PL) to the spinal cord in the mouse by injecting the retrograde tracer fluoro-gold to different levels of the spinal cord and injecting the anterograde tracer biotinylated dextran amine into PL. We found that PL projects to the entire spinal cord with obvious contralateral predominance - 420 neurons projected to the contralateral cervical cord and 270 to the contralateral lumbar cord. Fibers from PL descended in the dorsolateral funiculus on the contralateral side and terminated in laminae 5, 6, 7, and to a lesser extent in the dorsal and ventral horns. A smaller number of fibers also descended in the ventral funiculus on the ipsilateral side and terminated in laminae 7, 8 and, to a lesser extent in lamina 9. The present study is the first demonstration of the PL fiber termination in the spinal cord in mammals. The PL projection to the spinal cord may be involved in vocalization and locomotion.
Keyword Anterograde tracing
Fluoro-gold
Paralemniscal nucleus
Retrograde tracing
Spinal cord
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Queensland Brain Institute Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 3 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 27 Oct 2014, 15:27:24 EST by Sylvie Pichelin on behalf of Scholarly Communication and Digitisation Service