Hypovitaminosis D and morbidity in critical illness: is there proof beyond reasonable doubt?

Venkatesh, Bala and Nair, Priya (2014) Hypovitaminosis D and morbidity in critical illness: is there proof beyond reasonable doubt?. Critical Care, 18 3: 1-3. doi:10.1186/cc13863

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Author Venkatesh, Bala
Nair, Priya
Title Hypovitaminosis D and morbidity in critical illness: is there proof beyond reasonable doubt?
Journal name Critical Care   Check publisher's open access policy
ISSN 1466-609X
Publication date 2014-05-08
Year available 2014
Sub-type Editorial
DOI 10.1186/cc13863
Open Access Status File (Publisher version)
Volume 18
Issue 3
Start page 1
End page 3
Total pages 3
Place of publication London, United Kingdom
Publisher BioMed Central
Collection year 2015
Language eng
Abstract Vitamin D is recognized to have important actions outside its well-recognized role in musculoskeletal health. These include antimicrobial action, anti-inflammatory, and cardio-protective properties. A high prevalence of vitamin D deficiency and its association with adverse clinical outcomes have now been widely documented in observational studies in the critically ill. These studies of association, however, do not necessarily imply causation, as vitamin D deficiency may be merely a marker of higher illness severity and consequently poorer outcomes. This issue can be clarified only by undertaking high-quality randomized controlled trials of vitamin D supplementation in this vulnerable population.
Keyword Vitamin D deficiency
Intensive care unit
Ill patients
Mortality
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Editorial
Collections: Non HERDC
School of Medicine Publications
 
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