EEG Generator—A Model of Potentials in a Volume Conductor

Avitan, Lilach, Teicher, Mina and Abeles, Moshe (2009) EEG Generator—A Model of Potentials in a Volume Conductor. Journal of Neurophysiology, 102 5: 3046-3059. doi:10.1152/jn.91143.2008

Author Avitan, Lilach
Teicher, Mina
Abeles, Moshe
Title EEG Generator—A Model of Potentials in a Volume Conductor
Journal name Journal of Neurophysiology   Check publisher's open access policy
ISSN 0022-3077
Publication date 2009
Year available 2009
Sub-type Article (original research)
DOI 10.1152/jn.91143.2008
Open Access Status
Volume 102
Issue 5
Start page 3046
End page 3059
Total pages 14
Place of publication Bethesda, MD United States
Publisher American Physiological Society
Collection year 2009
Language eng
Formatted abstract
EEG generator-a model of potentials in a volume conductor. The potential recorded over the cortex electro-corticogram (ECoG) or over the scalp [electroencephalograph (EEG)] derives from the activity of many sources known as "EEG generators." The recorded amplitude is basically a function of the unitary potential of a generator and the statistical relationship between different EEG generators in the recorded population. In this study, we first suggest a new definition of the EEG generator. We use the theory of potentials in a volume conductor and model the contribution of a single synapse activated to the surface potential. We then model the contribution of the generator to the surface potential. Once the generator and its contribution are well defined, we can quantitatively assess the degree of synchronization among generators. The measures obtained by the model for a real life scenario of a group of generators organized in a specific statistical way were consistent with the expected values that were reported experimentally. The study sheds new light on macroscopic modeling approaches which make use of mean soma membrane potential. We showed major contribution of activity of superficial apical synapses to the ECoG signal recorded relative to lower somatic or basal synapses activity.
Keyword Coupled inhibitory neurons
Cerebral cortex
Sensorimotor cortex
Electrical activity
Spindle waves
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes For ERA

Document type: Journal Article
Sub-type: Article (original research)
Collection: Queensland Brain Institute Publications
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 11 times in Scopus Article | Citations
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Created: Fri, 24 Oct 2014, 13:29:12 EST by Debra McMurtrie on behalf of Queensland Brain Institute