Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides

Cant, Alastair A., Bhalla, Rajiv, Pimlott, Sally L. and Sutherland, Andrew (2012) Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides. Chemical Communications, 48 33: 3993-3995. doi:10.1039/c2cc30956d


Author Cant, Alastair A.
Bhalla, Rajiv
Pimlott, Sally L.
Sutherland, Andrew
Title Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides
Journal name Chemical Communications   Check publisher's open access policy
ISSN 1359-7345
1364-548X
Publication date 2012-04-25
Sub-type Article (original research)
DOI 10.1039/c2cc30956d
Volume 48
Issue 33
Start page 3993
End page 3995
Total pages 3
Place of publication Cambridge, United Kingdom
Publisher RSC Publications
Language eng
Abstract A fast and efficient nickel-catalysed iodination reaction of aryl and heteroaryl bromides has been developed. The transformation was found to be general for a wide range of substrates and was used for the synthesis of iodo-PK11195, an imaging agent of Alzheimer's disease and iniparib, a compound used in the treatment of breast cancer.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
 
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Created: Thu, 02 Oct 2014, 23:23:33 EST by Shona Osborne on behalf of Centre for Advanced Imaging