High resolution myocardial first-pass perfusion imaging with extended anatomic coverage

Staeb, Daniel, Wech, Tobias, Breuer, Felix A., Weng, Andreas Max, Ritter, Christian Oliver, Hahn, Dietbert and Koestler, Herbert (2014) High resolution myocardial first-pass perfusion imaging with extended anatomic coverage. Journal of Magnetic Resonance Imaging, 39 6: 1575-1587. doi:10.1002/jmri.24303

Author Staeb, Daniel
Wech, Tobias
Breuer, Felix A.
Weng, Andreas Max
Ritter, Christian Oliver
Hahn, Dietbert
Koestler, Herbert
Title High resolution myocardial first-pass perfusion imaging with extended anatomic coverage
Journal name Journal of Magnetic Resonance Imaging   Check publisher's open access policy
ISSN 1522-2586
Publication date 2014-06
Year available 2013
Sub-type Article (original research)
DOI 10.1002/jmri.24303
Open Access Status
Volume 39
Issue 6
Start page 1575
End page 1587
Total pages 13
Place of publication Hoboken United States
Publisher John Wiley and Sons
Collection year 2015
Language eng
Subject 2741 Radiology Nuclear Medicine and imaging
Formatted abstract
To evaluate and to compare Parallel Imaging and Compressed Sensing acquisition and reconstruction frameworks based on simultaneous multislice excitation for high resolution contrast-enhanced myocardial first-pass perfusion imaging with extended anatomic coverage.

Materials and Methods
The simultaneous multislice imaging technique MS-CAIPIRINHA facilitates imaging with significantly extended anatomic coverage. For additional resolution improvement, equidistant or random undersampling schemes, associated with corresponding reconstruction frameworks, namely Parallel Imaging and Compressed Sensing can be used. By means of simulations and in vivo measurements, the two approaches were compared in terms of reconstruction accuracy. Comprehensive quality metrics were used, identifying statistical and systematic reconstruction errors.

The quality measures applied allow for an objective comparison of the frameworks. Both approaches provide good reconstruction accuracy. While low to moderate noise enhancement is observed for the Parallel Imaging approach, the Compressed Sensing framework is subject to systematic errors and reconstruction induced spatiotemporal blurring.

Both techniques allow for perfusion measurements with a resolution of 2.0 × 2.0 mm2 and coverage of six slices every heartbeat. Being not affected by systematic deviations, the Parallel Imaging approach is considered to be superior for clinical studies. 
Cardiac imaging
Compressed sensing
Myocardial perfusion
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Centre for Advanced Imaging Publications
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