Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infection

Clark, P. J., Thompson, A. J. V. and McHutchison, J. G. (2010) Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infection. Clinical Pharmacology and Therapeutics, 88 5: 708-711. doi:10.1038/clpt.2010.185


Author Clark, P. J.
Thompson, A. J. V.
McHutchison, J. G.
Title Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infection
Journal name Clinical Pharmacology and Therapeutics   Check publisher's open access policy
ISSN 0009-9236
1532-6535
Publication date 2010
Year available 2010
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1038/clpt.2010.185
Open Access Status
Volume 88
Issue 5
Start page 708
End page 711
Total pages 4
Place of publication Hoboken, NJ United States
Publisher John Wiley and Sons Inc
Collection year 2010
Language eng
Subject 3004 Pharmacology
2736 Pharmacology (medical)
Formatted abstract
As more pharmacogenomic insights into diseases and their treatments and toxicities are published each year, the challenge arises to incorporate such insights into clinical practice and drug development.1 For instance, recent genomic discoveries related to hepatitis C offer a challenge to clinicians, researchers, and health administrators to translate this information into knowledge in order to develop safer and more effective therapeutic strategies for all patients.
Keyword Genetic Polymorphism
Interferon A
Hepatitis C virus infection
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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