Molecular epidemiology of NDM-1-producing Enterobacteriaceae and Acinetobacter baumannii isolates from Pakistan

Sartor, Anna L., Raza, Muhammad W., Abbasi, Shahid A., Day, Kathryn M., Perry, John D., Paterson, David L. and Sidjabat, Hanna E. (2014) Molecular epidemiology of NDM-1-producing Enterobacteriaceae and Acinetobacter baumannii isolates from Pakistan. Antimicrobial Agents and Chemotherapy, 58 9: 5589-5593. doi:10.1128/AAC.02425-14

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Author Sartor, Anna L.
Raza, Muhammad W.
Abbasi, Shahid A.
Day, Kathryn M.
Perry, John D.
Paterson, David L.
Sidjabat, Hanna E.
Title Molecular epidemiology of NDM-1-producing Enterobacteriaceae and Acinetobacter baumannii isolates from Pakistan
Formatted title
Molecular epidemiology of NDM-1-producing Enterobacteriaceae and Acinetobacter baumannii isolates from Pakistan
Journal name Antimicrobial Agents and Chemotherapy   Check publisher's open access policy
ISSN 0066-4804
1098-6596
Publication date 2014-09
Year available 2014
Sub-type Article (original research)
DOI 10.1128/AAC.02425-14
Open Access Status File (Publisher version)
Volume 58
Issue 9
Start page 5589
End page 5593
Total pages 5
Place of publication Washington, DC United States
Publisher American Society for Microbiology
Collection year 2015
Language eng
Subject 2736 Pharmacology (medical)
3004 Pharmacology
2725 Infectious Diseases
Abstract The molecular epidemiology of 66 NDM-producing isolates from 2 Pakistani hospitals was investigated, with their genetic relatedness determined using repetitive sequence-based PCR (Rep-PCR). PCR-based replicon typing and screening for antibiotic resistance genes encoding carbapenemases, other β-lactamases, and 16S methylases were also performed. Rep-PCR suggested a clonal spread of Enterobacter cloacae and Escherichia coli. A number of plasmid replicon types were identified, with the incompatibility A/C group (IncA/C) being the most common (78%). 16S methylase-encoding genes were coharbored in 81% of NDM-producing Enterobacteriaceae. Copyright
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2015 Collection
 
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Citation counts: TR Web of Science Citation Count  Cited 9 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 10 times in Scopus Article | Citations
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