Surface enhanced Raman scattering of brilliant green on Ag nanoparticles and applications in living cells as optical probes

Wang, Yuling, Li, Dan, Li, Peicai, Wang, Weidong, Ren, Wen, Dong, Shaojun and Wang, Erkang (2007) Surface enhanced Raman scattering of brilliant green on Ag nanoparticles and applications in living cells as optical probes. Journal of Physical Chemistry C, 111 45: 16833-16839. doi:10.1021/jp074519u


Author Wang, Yuling
Li, Dan
Li, Peicai
Wang, Weidong
Ren, Wen
Dong, Shaojun
Wang, Erkang
Title Surface enhanced Raman scattering of brilliant green on Ag nanoparticles and applications in living cells as optical probes
Journal name Journal of Physical Chemistry C   Check publisher's open access policy
ISSN 1932-7447
1932-7455
Publication date 2007-11-01
Sub-type Article (original research)
DOI 10.1021/jp074519u
Open Access Status Not yet assessed
Volume 111
Issue 45
Start page 16833
End page 16839
Total pages 7
Place of publication Washington, DC, United States
Publisher American Chemical Society
Language eng
Formatted abstract
In this article, surface enhanced Raman scattering (SERS) of different concentrations of brilliant green (BG) on Ag nanoparticles (AgNPs) has been investigated. The results indicate that only 10-6 M BG can be detected on AgNPs while as low as 10-12 M BG can be detected upon the activation of AgNPs by chloride ions. The additional improvement of the detection of BG mainly derives from the increase of the electromagnetic field around AgNPs and partially from the reorientation of BG on AgNPs induced by chloride ions, which was proved by the different spectra feature in the two systems. Adsorption of BG on AgNPs has also been demonstrated in applications of living cells as optical probes based on SERS, indicating that dye-AgNPs can probe the local environment in the living cells. The related cytotoxicity measurements demonstrated that BG-AgNPs produced little cytotoxicity to the cells, which shows great potential in biomedical applications of BG labeled-AgNPs for SERS nanosensors in cells as optical probes. Meanwhile, SERS spectra of BG on AgNPs in the presence chloride ions are expected to be used in living cells as more sensitive optical probes.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
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