Femtogram detection of cytokines in a direct dot-blot assay using SERS microspectroscopy and hydrophilically stabilized Au-Ag nanoshells

Wang, Yuling, Salehi, Mohammad, Schutz, Max and Schlucker, Sebastian (2014) Femtogram detection of cytokines in a direct dot-blot assay using SERS microspectroscopy and hydrophilically stabilized Au-Ag nanoshells. Chemical Communications, 50 21: 2711-2714. doi:10.1039/c3cc48633h


Author Wang, Yuling
Salehi, Mohammad
Schutz, Max
Schlucker, Sebastian
Title Femtogram detection of cytokines in a direct dot-blot assay using SERS microspectroscopy and hydrophilically stabilized Au-Ag nanoshells
Journal name Chemical Communications   Check publisher's open access policy
ISSN 1359-7345
1364-548X
Publication date 2014-03-01
Year available 2013
Sub-type Article (original research)
DOI 10.1039/c3cc48633h
Open Access Status DOI
Volume 50
Issue 21
Start page 2711
End page 2714
Total pages 4
Place of publication Cambridge United Kingdom
Publisher R S C Publications
Collection year 2015
Language eng
Subject 2506 Metals and Alloys
2505 Materials Chemistry
2508 Surfaces, Coatings and Films
2504 Electronic, Optical and Magnetic Materials
2503 Ceramics and Composites
1503 Business and Management
1600 Chemistry
Abstract Rapid parallel detection of two cytokines (IL-6 and IL-8) with femtogram sensitivity in a simple direct dot-blot assay is demonstrated. The microspectroscopic SERS acquisition scheme employs rationally designed, hydrophilically stabilized Au-Ag nanoshells as SERS labels, which are optimized for signal enhancement upon red laser excitation.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Australian Institute for Bioengineering and Nanotechnology Publications
 
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