Phylogenetic analyses provide the first insights into the evolution of OVATE family proteins in land plants

Liu, Di, Sun, Wei, Yuan,Yaowu, Zhang, Ning, Hayward, Alice, Liu, Yongliang and Wang, Ying (2014) Phylogenetic analyses provide the first insights into the evolution of OVATE family proteins in land plants. Annals of Botany, 113 7: 1219-1233. doi:10.1093/aob/mcu061

Author Liu, Di
Sun, Wei
Zhang, Ning
Hayward, Alice
Liu, Yongliang
Wang, Ying
Title Phylogenetic analyses provide the first insights into the evolution of OVATE family proteins in land plants
Journal name Annals of Botany   Check publisher's open access policy
ISSN 0305-7364
Publication date 2014-06-01
Sub-type Article (original research)
DOI 10.1093/aob/mcu061
Open Access Status
Volume 113
Issue 7
Start page 1219
End page 1233
Total pages 15
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Collection year 2015
Language eng
Formatted abstract
Background and Aims: The OVATE gene encodes a nuclear-localized regulatory protein belonging to a distinct family of plant-specific proteins known as the OVATE family proteins (OFPs). OVATE was first identified as a key regulator of fruit shape in tomato, with nonsense mutants displaying pear-shaped fruits. However, the role of OFPs in plant development has been poorly characterized.

Methods: Public databases were searched and a total of 265 putative OVATE protein sequences were identified from 13 sequenced plant genomes that represent the major evolutionary lineages of land plants. A phylogenetic analysis was conducted based on the alignment of the conserved OVATE domain from these 13 selected plant genomes. The expression patterns of tomato SlOFP genes were analysed via quantitative real-time PCR. The pattern of OVATE gene duplication resulting in the expansion of the gene family was determined in arabidopsis, rice and tomato.

Key Results: Genes for OFPs were found to be present in all the sampled land plant genomes, including the early-diverged lineages, mosses and lycophytes. Phylogenetic analysis based on the amino acid sequences of the conserved OVATE domain defined 11 sub-groups of OFPs in angiosperms. Different evolutionary mechanisms are proposed for OVATE family evolution, namely conserved evolution and divergent expansion. Characterization of the AtOFP family in arabidopsis, the OsOFP family in rice and the SlOFP family in tomato provided further details regarding the evolutionary framework and revealed a major contribution of tandem and segmental duplications towards expansion of the OVATE gene family.

Conclusions: This first genome-wide survey on OFPs provides new insights into the evolution of the OVATE protein family and establishes a solid base for future functional genomics studies on this important but poorly characterized regulatory protein family in plants.
Keyword Angiosperm
Arabidopsis thaliana
Land plants
Oryza sativa
OVATE family proteins
Phylogenetic analyses
Segmental duplication
Solanum lycopersicum
Tandem duplication
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Queensland Alliance for Agriculture and Food Innovation
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Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 25 Aug 2014, 17:25:59 EST by Dr Alice Hayward on behalf of Centre for Plant Science