A state of art review on vardenafil in men with erectile dysfunction and associated underlying diseases

Chung, Eric and Brock, Gerald B. (2011) A state of art review on vardenafil in men with erectile dysfunction and associated underlying diseases. Expert Opinion on Pharmacotherapy, 12 8: 1341-1348. doi:10.1517/14656566.2011.584064


Author Chung, Eric
Brock, Gerald B.
Title A state of art review on vardenafil in men with erectile dysfunction and associated underlying diseases
Journal name Expert Opinion on Pharmacotherapy   Check publisher's open access policy
ISSN 1465-6566
1744-7666
Publication date 2011
Year available 2011
Sub-type Article (original research)
DOI 10.1517/14656566.2011.584064
Open Access Status
Volume 12
Issue 8
Start page 1341
End page 1348
Total pages 8
Place of publication London, United Kingdom
Publisher Informa Healthcare
Collection year 2012
Language eng
Subject 2736 Pharmacology (medical)
3004 Pharmacology
Abstract Introduction: Erectile dysfunction (ED) is a common male sexual disorder among men.Many governing bodies advocate the use of oral PDE5 inhibitors as a first-line therapy for ED.The clinical efficacy of these PDE5 inhibitors has been demonstrated in a number of placebo-controlled trials and reported by many systematic reviews on the effectiveness of PDE5 inhibitors in restoring the erectile function and improved frequency of successful sexual intercourse attempts across different spectra of underlying diseases.Areas covered: This review article examines the drug profile of vardenafil and its role in restoring erectile function; highlights a number of clinical trials on vardenafil in men with underlying cardiovascular and metabolic conditions as well as in post-radical prostatectomy cases; and addresses the efficacy of vardenafil in comparison with other PDE5 inhibitors.Expert opinion: Given the multi-factorial nature of ED, a holistic approach should be taken when dealing with ED patients.There is a need for long-term surveillance and management of underlying medical conditions, and despite the strict adherence to all the necessary steps to maximize its efficacy, PDE5 inhibitors could still fail due to the potential drug intolerance, progression of underlying disease or development of medical conditions.
Keyword Erectile Dysfunction
PDE5 inhibitors
Vardenafil
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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