Calcium signaling in axon guidance

Sutherland, Daniel J., Pujic, Zac and Goodhill, Geoffrey J. (2014) Calcium signaling in axon guidance. Trends in Neurosciences, 37 8: 424-432. doi:10.1016/j.tins.2014.05.008

Author Sutherland, Daniel J.
Pujic, Zac
Goodhill, Geoffrey J.
Title Calcium signaling in axon guidance
Journal name Trends in Neurosciences   Check publisher's open access policy
ISSN 0169-5347
Publication date 2014
Year available 2014
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.tins.2014.05.008
Open Access Status
Volume 37
Issue 8
Start page 424
End page 432
Total pages 9
Place of publication Kidlington, Oxford, United Kingdom
Publisher Elsevier
Collection year 2015
Language eng
Abstract Guidance of axons to their targets in the developing nervous system requires a myriad of downstream signaling molecules to coordinate growth cone movement. One of the most important of these is calcium, and over the past few years many new insights have been gained into the role of calcium in axon guidance. In this review we focus on mechanisms of calcium entry into the growth cone and its downstream effects on both growth cone motility and turning. We particularly highlight the role of calcium concentrations in determining attractive versus repulsive responses to graded guidance cues, and their role in guidance by the morphogen Wnt5a.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: School of Mathematics and Physics
Queensland Brain Institute Publications
Official 2015 Collection
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 13 times in Scopus Article | Citations
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Created: Tue, 12 Aug 2014, 04:31:26 EST by System User on behalf of Queensland Brain Institute