Design of a highly sensitive and specific nucleotide sensor based on photon upconverting particles

Zhang P., Rogelj S., Nguyen K. and Wheeler D. (2006) Design of a highly sensitive and specific nucleotide sensor based on photon upconverting particles. Journal of the American Chemical Society, 128 38: 12410-12411. doi:10.1021/ja0644024


Author Zhang P.
Rogelj S.
Nguyen K.
Wheeler D.
Title Design of a highly sensitive and specific nucleotide sensor based on photon upconverting particles
Journal name Journal of the American Chemical Society   Check publisher's open access policy
ISSN 0002-7863
Publication date 2006-09-27
Sub-type Article (original research)
DOI 10.1021/ja0644024
Volume 128
Issue 38
Start page 12410
End page 12411
Total pages 2
Language eng
Subject 1600 Chemistry
Abstract We have designed and developed a novel sensor that reports the presence of specific nucleic acids in solutions, based on photon upconverting particles. The significantly high signal-to-noise ratio of photon upconverting particles leads to high sensitivity of the sensor. The sensor does not suffer from photobleaching. It also displays high specificity and self-calibrating capability. We expect nucleotide sensors of this type to be effective for applications in both DNA/RNA detection and protein-DNA/RNA interaction studies. Copyright
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
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Citation counts: TR Web of Science Citation Count  Cited 158 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 160 times in Scopus Article | Citations
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