The validity of the menopause-specific quality of life questionnaire in women with type 2 diabetes

Hasan, S. S., Ahmadi, K., Santigo, R. and Ahmed, S. I. (2014) The validity of the menopause-specific quality of life questionnaire in women with type 2 diabetes. Climacteric, 17 4: 456-464. doi:10.3109/13697137.2013.864269


Author Hasan, S. S.
Ahmadi, K.
Santigo, R.
Ahmed, S. I.
Title The validity of the menopause-specific quality of life questionnaire in women with type 2 diabetes
Journal name Climacteric   Check publisher's open access policy
ISSN 1473-0804
1369-7137
Publication date 2014
Year available 2014
Sub-type Article (original research)
DOI 10.3109/13697137.2013.864269
Open Access Status
Volume 17
Issue 4
Start page 456
End page 464
Total pages 9
Place of publication London, United Kingdom
Publisher Informa Healthcare
Collection year 2015
Language eng
Abstract Objectives To examine the validity and reliability of the Menopause-specific Quality of Life (MENQOL) questionnaire in a sample of women with diabetes in Malaysia, with the secondary aim of determining whether MENQOL domain scores were associated with depression and diabetes. Methods A total of 337 postmenopausal women (241 with diabetes, 96 controls) were evaluated. Construct validity was evaluated using principal components analysis (PCA) and comparing scale items against the mental component score of the Short Form-12 (SF-12 MCS), and against the Center for Epidemiologic Studies Depression Scale 10 (CES-D 10). Consistency assessment was conducted using Cronbach's α. Results The internal consistencies for the physical (PHS), psychosocial (PS), sexual (VSS) and vasomotor domains were 0.86, 0.79, 0.79 and 0.70, and 0.90 for the full scale of MENQOL. PCA revealed a four-factorial model. Diabetes and non-diabetes subjects experienced their first period (13.25 vs. 13.10 years, p = 0.680) and achieved menopause around the same age (49.35 vs. 48.87 years, p = 0.426). We found significant variations in the MENQOL's PHS and PS domain scores that could be explained by SF-12 PCS (25%) and SF-12 MCS (20%) sub-scales. The validity of the MENQOL domains was demonstrated through significant associations with the equivalent SF-12 MCS and PCS subscales. The PS domain of the MENQOL also predicted the likelihood of symptoms of depression (1.42, 95% confidence interval 1.01-2.02). Conclusions This study confirms the validity and internal consistency of the MENQOL questionnaire for measuring quality of life in postmenopausal women with diabetes, suggesting that the instrument can be used to screen people for menopausal symptoms.
Keyword Diabetes
Menopause
Quality Of Life
Validity
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Pharmacy Publications
 
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