Restriction endonuclease analysis of group B streptococcal isolates from two distinct geographical regions

Ellis, S., Kotiw, M. and Garland, S. M. (1996) Restriction endonuclease analysis of group B streptococcal isolates from two distinct geographical regions. Journal of Hospital Infection, 33 4: 279-287. doi:10.1016/S0195-6701(96)90014-6


Author Ellis, S.
Kotiw, M.
Garland, S. M.
Title Restriction endonuclease analysis of group B streptococcal isolates from two distinct geographical regions
Journal name Journal of Hospital Infection   Check publisher's open access policy
ISSN 0195-6701
1532-2939
Publication date 1996-08-01
Sub-type Article (original research)
DOI 10.1016/S0195-6701(96)90014-6
Open Access Status Not Open Access
Volume 33
Issue 4
Start page 279
End page 287
Total pages 9
Place of publication London, United Kingdom
Publisher WB Saunders Co.
Language eng
Abstract This study examined isolates of group B streptococci (GBS) by latex seroagglutination and restriction endonuclease analysis (REA). REA analysis was performed with high- and low-frequency cutting enzymes, and fragments were resolved by linear and pulsed-field gel electrophoresis (PFGE), respectively. GBS isolates were derived from a regional acute-care hospital and a tertiary referral obstetric hospital. The most common serotype isolated at the general hospital was serotype V (42%). A high incidence of this serotype V was associated with wound infections, but there was no predominant REA profile. Serotype III was the most common from the obstetric hospital (41%). The majority of these isolates were associated with neonatal GBS infection and there was a predominant restriction pattern. Analysis of restriction patterns of GBS isolated from individual mother/baby pairs revealed common patterns. These data extend the evidence for vertical transmission of GBS and clones of serotype III GBS with increased pathogenic potential.
Keyword Group B streptococcus
Pulsed-field gel electrophoresis
Neonatal infection
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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