Variability in the management of lithium poisoning

Roberts, Darren M. and Gosselin, Sophie (2014) Variability in the management of lithium poisoning. Seminars in Dialysis, 27 4: 390-394. doi:10.1111/sdi.12235

Author Roberts, Darren M.
Gosselin, Sophie
Title Variability in the management of lithium poisoning
Journal name Seminars in Dialysis   Check publisher's open access policy
ISSN 1525-139X
Publication date 2014-07
Year available 2014
Sub-type Article (original research)
DOI 10.1111/sdi.12235
Open Access Status
Volume 27
Issue 4
Start page 390
End page 394
Total pages 5
Place of publication Hoboken, United States
Publisher Wiley-Blackwell Publishing
Collection year 2015
Language eng
Abstract Three patterns of lithium poisoning are recognized: acute, acute-on-chronic, and chronic. Intravenous fluids with or without an extracorporeal treatment are the mainstay of treatment; their respective roles may differ depending on the mode of poisoning being treated. Recommendations for treatment selection are available but these are based on a small number of observational studies and their uptake by clinicians is not known. Clinician decision-making in the treatment of four cases of lithium poisoning was assessed at a recent clinical toxicology meeting using an audience response system. Variability in treatment decisions was evident in addition to discordance with published recommendations. Participants did not consistently indicate that hemodialysis was the first-line treatment, instead opting for a conservative approach, and continuous modalities were viewed favorably; this is in contrast to recommendations in some references. The development of multidisciplinary consensus guidelines may improve the management of patients with lithium poisoning but prospective randomized controlled trials are required to more clearly define the role of extracorporeal treatments.
Keyword Lithium poisoning
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published July‚ÄďAugust 2014

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
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