Clathrin-independent pathways of endocytosis

Mayor, Satyajit, Parton, Robert G. and Donaldson, Julie G. (2014) Clathrin-independent pathways of endocytosis. Cold Spring Harbor Perspectives in Biology, 6 6: 1-20. doi:10.1101/cshperspect.a016758

Author Mayor, Satyajit
Parton, Robert G.
Donaldson, Julie G.
Title Clathrin-independent pathways of endocytosis
Journal name Cold Spring Harbor Perspectives in Biology   Check publisher's open access policy
ISSN 1943-0264
Publication date 2014-06
Year available 2014
Sub-type Article (original research)
DOI 10.1101/cshperspect.a016758
Open Access Status
Volume 6
Issue 6
Start page 1
End page 20
Total pages 20
Place of publication Woodbury, NY United States
Publisher Cold Spring Harbor Laboratory Press
Collection year 2015
Language eng
Abstract There are many pathways of endocytosis at the cell surface that apparently operate at the same time.With the advent of newmolecular genetic and imaging tools, an understanding of the differentways bywhich a cellmay endocytose cargo is increasing by leaps and bounds. In this review we explore pathways of endocytosis that occur in the absence of clathrin. These are referred to as clathrin-independent endocytosis (CIE). Here we primarily focus on those pathways that function at the small scale in which some have distinct coats (caveolae) and others function in the absence of specific coated intermediates. We follow the trafficking itineraries of the material endocytosed by these pathways and finally discuss the functional roles that these pathways play in cell and tissue physiology. It is likely that these pathways will play key roles in the regulation of plasma membrane area and tension and also control the availability of membrane during cell migration.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Institute for Molecular Bioscience - Publications
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Citation counts: TR Web of Science Citation Count  Cited 28 times in Thomson Reuters Web of Science Article | Citations
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