Sex differences in symptom presentation in acute myocardial infarction: a systematic review and meta-analysis

Coventry, Linda L., Finn, Judith and Bremner, Alexandra P. (2011) Sex differences in symptom presentation in acute myocardial infarction: a systematic review and meta-analysis. Heart and Lung: The Journal of Acute and Critical Care, 40 6: 477-491. doi:10.1016/j.hrtlng.2011.05.001


Author Coventry, Linda L.
Finn, Judith
Bremner, Alexandra P.
Title Sex differences in symptom presentation in acute myocardial infarction: a systematic review and meta-analysis
Journal name Heart and Lung: The Journal of Acute and Critical Care   Check publisher's open access policy
ISSN 0147-9563
1527-3288
Publication date 2011-11
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.hrtlng.2011.05.001
Open Access Status
Volume 40
Issue 6
Start page 477
End page 491
Total pages 15
Place of publication Philadelphia, United States
Publisher Mosby
Language eng
Formatted abstract
Background: Recognition of sex differences in symptom presentation of acute myocardial infarction (AMI) is important for timely clinical diagnosis. This review examined whether women are equally as likely as men to present with chest pain.

Methods: We conducted a systematic review and meta-analysis of English language research articles published between 1990 and 2009.

Results: Meta-analysis showed women with AMI had lower odds and a lower rate of presenting with chest pain than men (odds ratio .63; 95% confidence interval, .59–.68; risk ratio .93; 95% confidence interval, .91–.95). Women were significantly more likely than men to present with fatigue, neck pain, syncope, nausea, right arm pain, dizziness, and jaw pain.

Conclusion: Health campaigns on symptom presentation of AMI should continue to promote chest pain as the cardinal symptom of AMI, but also reflect a wider spectrum of possible symptoms and highlight potential differences in symptom presentation between men and women. 
Keyword Acute myocardial infarction
Meta-analysis
Sex differences
Symptom presentation
Systematic review
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes Published November–December 2011.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Nursing, Midwifery and Social Work Publications
 
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Created: Thu, 17 Jul 2014, 09:48:54 EST by Vicki Percival on behalf of School of Nursing, Midwifery and Social Work