Noninvasive tools to assess liver disease

Clark, Paul J. and Patel, Keyur (2011) Noninvasive tools to assess liver disease. Current Opinion in Gastroenterology, 27 3: 210-216. doi:10.1097/MOG.0b013e328343e9a3


Author Clark, Paul J.
Patel, Keyur
Title Noninvasive tools to assess liver disease
Journal name Current Opinion in Gastroenterology   Check publisher's open access policy
ISSN 0267-1379
1531-7056
Publication date 2011
Year available 2011
Sub-type Article (original research)
DOI 10.1097/MOG.0b013e328343e9a3
Open Access Status
Volume 27
Issue 3
Start page 210
End page 216
Total pages 7
Place of publication Philadelphia, PA United States
Publisher Lippincott Williams and Wilkins
Collection year 2012
Language eng
Subject 2715 Gastroenterology
Abstract Purpose of review: To improve understanding of recent developments in the noninvasive assessment of fibrosis and their potential clinical application to a range of chronic liver diseases. Recent findings: Many noninvasive tests have evolved from their primary validation in chronic hepatitis C virus (HCV) infection to integration into clinical management algorithms for chronic liver disease of varying cause. Recent studies consider the use of these techniques in sequence or in combination, and compare the performance of serum and imaging-based noninvasive techniques to identify patients with significant fibrosis, or those at most risk of clinical sequelae from advanced-stage disease. Methods developed in chronic hepatitis C have now been applied in different chronic liver diseases, including nonalcoholic fatty liver disease, alcoholic liver disease, HIV/HCV co-infection and primary biliary cirrhosis. A number of new management algorithms have been developed to facilitate the integration of noninvasive techniques into clinical practice. Summary: Noninvasive tools to assess liver diseases continue to evolve. New imaging technologies have been developed. Existing biomarkers and imaging modalities have been better integrated into clinical practice algorithms, and applied to different chronic liver diseases. Noninvasive techniques will likely continue to be refined and play an important role in the future management of patients with chronic liver disease.
Keyword Biomarkers
Biopsy
Elastography
Fibrosis
Imaging
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Thu, 17 Jul 2014, 09:20:46 EST by Anthony Yeates on behalf of Medicine - Princess Alexandra Hospital