Developmental defects of enamel and dentine: Challenges for basic science research and clinical management

Seow, W. K. (2014) Developmental defects of enamel and dentine: Challenges for basic science research and clinical management. Australian Dental Journal, 59 Suppl. 1: 143-154. doi:10.1111/adj.12104


Author Seow, W. K.
Title Developmental defects of enamel and dentine: Challenges for basic science research and clinical management
Journal name Australian Dental Journal   Check publisher's open access policy
ISSN 0045-0421
1834-7819
Publication date 2014
Year available 2014
Sub-type Article (original research)
DOI 10.1111/adj.12104
Open Access Status
Volume 59
Issue Suppl. 1
Start page 143
End page 154
Total pages 12
Place of publication Chichester, West Sussex, United Kingdom
Publisher Blackwell Publishing
Collection year 2015
Language eng
Subject 3500 Dentistry
Abstract Abnormalities of enamel and dentine are caused by a variety of interacting factors ranging from genetic defects to environmental insults. The genetic changes associated with some types of enamel and dentine defects have been mapped, and many environmental influences, including medical illnesses that can damage enamel and dentine have been identified. Developmental enamel defects may present as enamel hypoplasia or hypomineralization while dentine defects frequently demonstrate aberrant calcifications and abnormalities of the dentine-pulp complex. Clinically, developmental enamel defects often present with problems of discolouration and aesthetics, tooth sensitivity, and susceptibility to caries, wear and erosion. In contrast, dentine defects are a risk for endodontic complications resulting from dentine hypomineralization and pulpal abnormalities. The main goals of managing developmental abnormalities of enamel and dentine are early diagnosis and improvement of appearance and function by preserving the dentition and preventing complications. However, despite major advances in scientific knowledge regarding the causes of enamel and dentine defects, further research is required in order to translate the knowledge gained in the basic sciences research to accurate clinical diagnosis and successful treatment of the defects.
Keyword Dentine
Enamel
Hypomineralization
Hypoplasia
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Dentistry Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 12 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 17 times in Scopus Article | Citations
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