Expression patterns of connexins in Merkel cell carcinoma and adjacent epidermis

Haass, Nikolas K., Houdek, Pia, Brandner, Johanna M. and Moll, Ingrid (2003). Expression patterns of connexins in Merkel cell carcinoma and adjacent epidermis. In Klaus I. Baumann, Zdenek Halata and Ingrid Moll (Ed.), The Merkel Cell: Structure-Development-Function-Cancerogenesis. Proceedings of the International Merkel Cell Symposium, Hamburg 2002 (pp. 219-222) Berlin, Germany: Springer-Verlag. doi:10.1007/978-3-662-10358-6_31


Author Haass, Nikolas K.
Houdek, Pia
Brandner, Johanna M.
Moll, Ingrid
Title of chapter Expression patterns of connexins in Merkel cell carcinoma and adjacent epidermis
Title of book The Merkel Cell: Structure-Development-Function-Cancerogenesis. Proceedings of the International Merkel Cell Symposium, Hamburg 2002
Place of Publication Berlin, Germany
Publisher Springer-Verlag
Publication Year 2003
Sub-type Research book chapter (original research)
DOI 10.1007/978-3-662-10358-6_31
Open Access Status
ISBN 9783642055744
9783662103586
Editor Klaus I. Baumann
Zdenek Halata
Ingrid Moll
Start page 219
End page 222
Total pages 4
Language eng
Formatted Abstract/Summary
Alterations in cell—cell communication play an important role in carcinogene­sis. The specificity of communication is controlled by the type of connexins (Cx) forming gap junctions (GJ).

In this work, we show an induction of Cx30 and Cx26 in normal interfollicular epidermis adjacent to Merkel cell carcinoma. This observation and previous investigations of gap junctional communication in other malignant skin tumours give a hint that the change of the composition of gap junctions in the epidermis adjacent to malignant skin tumours may play a role in their metastasization.
Q-Index Code B1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Book Chapter
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Created: Mon, 02 Jun 2014, 15:34:28 EST by Nikolas Haass on behalf of UQ Diamantina Institute