Characterization of murine gammaherpesvirus 68 glycoprotein B

Lopes, Filipa B., Colaco, Susanna, May, Janet S. and Stevenson, Philip G. (2004) Characterization of murine gammaherpesvirus 68 glycoprotein B. Journal of Virology, 78 23: 13370-13375. doi:10.1128/JVI.78.23.13370-13375.2004

Author Lopes, Filipa B.
Colaco, Susanna
May, Janet S.
Stevenson, Philip G.
Title Characterization of murine gammaherpesvirus 68 glycoprotein B
Journal name Journal of Virology   Check publisher's open access policy
ISSN 0022-538X
Publication date 2004-12
Year available 2004
Sub-type Article (original research)
DOI 10.1128/JVI.78.23.13370-13375.2004
Open Access Status DOI
Volume 78
Issue 23
Start page 13370
End page 13375
Total pages 6
Place of publication Washington, DC, United States
Publisher American Society for Microbiology
Language eng
Subject 2403 Immunology
Abstract Murine gammaherpesvirus 68 (MHV-68) glycoprotein B (gB) was identified in purified virions by immunoblotting, immunoprecipitation, and immunoelectron microscopy. It was synthesized as a 120-kDa precursor in infected cells and cleaved into 65-kDa and 55-kDa disulfide-linked subunits close to the time of virion release. The N-linked glycans on the cleaved, virion gB remained partially endoglycosidase H sensitive. The processing of MHV-68 gB therefore appears similar to that of Kaposi's sarcoma-associated herpesvirus gB and human cytomegalovirus gB.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
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