Health-related quality of life in hospital inpatients with pressure ulceration: assessment using generic health-related quality of life measures

Essex, Holly N., Clark, Michael, Sims, Joyce, Warriner, Ann and Cullum, Nicky (2009) Health-related quality of life in hospital inpatients with pressure ulceration: assessment using generic health-related quality of life measures. Wound Repair and Regeneration, 17 6: 797-805. doi:10.1111/j.1524-475X.2009.00544.x


Author Essex, Holly N.
Clark, Michael
Sims, Joyce
Warriner, Ann
Cullum, Nicky
Title Health-related quality of life in hospital inpatients with pressure ulceration: assessment using generic health-related quality of life measures
Journal name Wound Repair and Regeneration   Check publisher's open access policy
ISSN 1524-475X
1067-1927
Publication date 2009-11
Sub-type Article (original research)
DOI 10.1111/j.1524-475X.2009.00544.x
Open Access Status
Volume 17
Issue 6
Start page 797
End page 805
Total pages 9
Place of publication Hoboken, NJ, United States
Publisher Wiley-Blackwell
Language eng
Formatted abstract
The objective of this study was to determine the impact of pressure ulceration on health-related quality of life (HRQoL) and to undertake a pilot study for a future larger study. The study comprised two parts. First, data from a large UK prospective cohort study were analyzed and the HRQoL of 218 people with pressure ulcers was compared with that of 2,289 people without ulcers using the Short Form-36 (SF-36) questionnaire. After adjusting for age, sex, and comorbidities, patients with pressure ulceration had significantly lower scores for both the physical (coefficient=−3.12, p<0.001) and mental (coefficient=−1.50, p=0.04) component summary scores of the SF-36. Second, a small pilot study was conducted to explore use of other tools. HRQoL was assessed in six patients with and 16 patients without pressure ulcers using the SF-36, the EQ-5D and a pain visual analog scale. SF-36 scores indicated that patients with pressure ulcers had significantly poorer physical functioning (d=22.3, p=0.001), role limitations due to physical problems (d=12.9, p=0.02), and vitality (d=20.6, p=0.04) than those without. EQ-5D scores were also poorer for patients with pressure ulceration, for both the visual analog scale (d=19.2, p=0.02) and the index (d=0.29, p=0.08). Patients with pressure ulceration had more perceived pain than those without; however, this difference was of borderline significance (d=−23.9, p=0.06). Pressure ulceration therefore has an impact on HRQoL that is measurable and persists after adjusting for potential confounding.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Nursing, Midwifery and Social Work Publications
 
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Created: Wed, 21 May 2014, 09:19:14 EST by Vicki Percival on behalf of School of Nursing, Midwifery and Social Work