There is a growing interest in the link between the developing brain and maximising outcomes in schools. Recent research indicates that students in many western countries tend to fall behind in ranking on global scales. Every three years, since 2000, the Organization for Economic Co-Operation and Development (OECD) has provided a comparative report on the rankings of the knowledge of 15 year-olds in mathematics, reading, and science. The 5th report, the 2012 Programme for International Student Assessment (PISA), was released late last year (OECD-PISA 2012). This report is based on results from 510,000 students in 65 countries, aged between 15.3 and 16.2 years, and is representative of 28 million students in this age group, globally, and 80% of the world economy. Demographic information was collected through questionnaires to students and school principals regarding the student’s background, the school, the learning environment, and school systems.