Digoxin prescription in the critically ill: an unpredictably loaded problem?

Mrara, B., Roberts, J. A. and Gowardman, J. (2013) Digoxin prescription in the critically ill: an unpredictably loaded problem?. Anaesthesia and Intensive Care, 41 3: 434-436.

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads
Author Mrara, B.
Roberts, J. A.
Gowardman, J.
Title Digoxin prescription in the critically ill: an unpredictably loaded problem?
Journal name Anaesthesia and Intensive Care   Check publisher's open access policy
ISSN 0310-057X
1448-0271
Publication date 2013-05
Sub-type Letter to editor, brief commentary or brief communication
Open Access Status
Volume 41
Issue 3
Start page 434
End page 436
Total pages 3
Place of publication Edgecliff, NSW, Australia
Publisher Australian Society of Anaesthetists
Collection year 2014
Language eng
Formatted abstract
A 64-year-old woman was admitted to the intensive care unit for management of septic shock from abdominal sepsis due to colonic perforation, for which a laparotomy and hemicolectomy had been performed. She had no prior cardiac history. On admission to the intensive care unit, she was shocked with sinus tachycardia requiring noradrenaline vasopressor support...

...We consider it possible that a drug interaction played a role in the elevated digoxin levels observed in this case, though we would consider drug interaction effects to be more likely during maintenance dosing. In conclusion, we advise a reduced digoxin loading dose in critically ill patients with reduced muscle mass taking medications with known interactions with digoxin.
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Letter to editor, brief commentary or brief communication
Collections: Non HERDC
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in Thomson Reuters Web of Science Article
Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Thu, 17 Apr 2014, 13:47:47 EST by Dr Jason Roberts on behalf of Anaesthesiology and Critical Care - RBWH