Update on nutritional status, body composition and growth in paediatric inflammatory bowel disease

Hill, Rebecca J. (2014) Update on nutritional status, body composition and growth in paediatric inflammatory bowel disease. World Journal of Gastroenterology, 20 12: 3191-3197. doi:10.3748/wjg.v20.i12.3191

Author Hill, Rebecca J.
Title Update on nutritional status, body composition and growth in paediatric inflammatory bowel disease
Journal name World Journal of Gastroenterology   Check publisher's open access policy
ISSN 2219-2840
Publication date 2014-03-28
Year available 2014
Sub-type Article (original research)
DOI 10.3748/wjg.v20.i12.3191
Open Access Status DOI
Volume 20
Issue 12
Start page 3191
End page 3197
Total pages 7
Place of publication Pleasanton, CA, United States
Publisher Baishideng Publishing Group
Collection year 2015
Language eng
Abstract Growth and nutritional status are important issues in paediatric inflammatory bowel disease (IBD). While linear growth is easy to assess, nutritional status is more complicated, with reports often compromised by the use of simple measures, such as weight and the body mass index, to assess nutritional status rather than more appropriate and sophisticated techniques to measure body composition. This review is an update on what is currently known about nutritional status as determined by body composition in paediatric IBD. Further, this review will focus on the impact of biologics on growth in paediatric IBD. Significant lean mass deficits have been reported in children with IBD compared with controls, and there is evidence these deficits persist over time. Furthermore, data imply that gender differences exist in body composition, both at diagnosis and in response to treatment. With respect to growth improvements following treatment with biologics, there are conflicting data. While some studies report enhancement of growth, others do not. The relationship between disease severity, impaired growth and the requirement for biologics needs to be considered when interpreting these data. However, key features associated with improvements in growth appear to be successful clinical response to treatment, patients in early stages of puberty, and the presence of growth failure at the onset of treatment.
Keyword Crohn's disease
Ulcerative colitis
Lean mass
Pubertal status
Inflammatory bowel disease
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
Queensland Children's Medical Research Institute Publications
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Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
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