Long-term follow-up of patients with idiopathic infantile hypercalcaemia

Huang J., Coman D., McTaggart S.J. and Burke J.R. (2006) Long-term follow-up of patients with idiopathic infantile hypercalcaemia. Pediatric Nephrology, 21 11: 1676-1680. doi:10.1007/s00467-006-0217-0

Author Huang J.
Coman D.
McTaggart S.J.
Burke J.R.
Title Long-term follow-up of patients with idiopathic infantile hypercalcaemia
Journal name Pediatric Nephrology   Check publisher's open access policy
ISSN 0931-041X
Publication date 2006
Sub-type Article (original research)
DOI 10.1007/s00467-006-0217-0
Open Access Status
Volume 21
Issue 11
Start page 1676
End page 1680
Total pages 5
Language eng
Subject 2727 Nephrology
2735 Pediatrics, Perinatology, and Child Health
Abstract Idiopathic infantile hypercalcaemia (IIH) is a rare disorder of unknown etiology that presents with hypercalcaemia in a child's first year of life. There is only a limited number of published reports of the natural history of this condition, and the long-term prognosis is largely unknown. The presentation, treatment and long-term follow-up of 11 children with IIH treated at our institution since 1993 are described. Hypercalcaemia resolved in the majority of children by the time they were 3 years of age, but nephrocalcinosis and persistent hypercalciuria were common, and, in some cases, urinary calcium excretion increased after initially becoming normal. This study suggests that clinical and biochemical abnormalities may persist for longer than previously reported and implies the need for ongoing surveillance of patients with IIH.
Keyword Hypercalcaemia
Idiopathic infantile hypercalcaemia
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
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