Generalized inverse imaging (GIN): Ultrafast fMRI with physiological noise correction

Boyacioglu, Rasim and Barth, Markus (2013) Generalized inverse imaging (GIN): Ultrafast fMRI with physiological noise correction. Magnetic Resonance in Medicine, 70 4: 962-971. doi:10.1002/mrm.24528

Author Boyacioglu, Rasim
Barth, Markus
Title Generalized inverse imaging (GIN): Ultrafast fMRI with physiological noise correction
Journal name Magnetic Resonance in Medicine   Check publisher's open access policy
ISSN 0740-3194
Publication date 2013
Year available 2013
Sub-type Article (original research)
DOI 10.1002/mrm.24528
Open Access Status
Volume 70
Issue 4
Start page 962
End page 971
Total pages 10
Place of publication Hoboken, NJ United States
Publisher Jossey Bass, Ed. and Pub.
Collection year 2014
Language eng
Subject 2741 Radiology Nuclear Medicine and imaging
Abstract An ultrafast functional magnetic resonance imaging (fMRI) technique, called generalized inverse imaging (GIN), is proposed, which combines inverse imaging with a phase constraint - leading to a less underdetermined reconstruction - and physiological noise correction. A single 3D echo planar imaging (EPI) prescan is sufficient to obtain the necessary coil sensitivity information and reference images that are used to reconstruct standard images, so that standard analysis methods are applicable. A moving dots stimulus paradigm was chosen to assess the performance of GIN. We find that the spatial localization of activation for GIN is comparable to an EPI protocol and that maximum z-scores increase significantly. The high temporal resolution of GIN (50 ms) and the acquisition of the phase information enable unaliased sampling and regression of physiological signals. Using the phase time courses obtained from the 32 channels of the receiver coils as nuisance regressors in a general linear model results in significant improvement of the functional activation, rendering the acquisition of external physiological signals unnecessary. The proposed physiological noise correction can in principle be used for other fMRI protocols, such as simultaneous multislice acquisitions, which acquire the phase information sufficiently fast and sample physiological signals unaliased.
Keyword brain
Ultrafast fMRI
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Centre for Advanced Imaging Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 8 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 5 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Thu, 20 Mar 2014, 09:14:09 EST by Ms Kate Rowe on behalf of Centre for Advanced Imaging