T1 mapping of the entire lung parenchyma: influence of the respiratory phase in healthy individuals

Stadler, Alfred, Jakob, Peter M., Griswold, Mark, Barth, Markus and Bankier, Alexander A. (2005) T1 mapping of the entire lung parenchyma: influence of the respiratory phase in healthy individuals. Journal of Magnetic Resonance Imaging, 21 6: 759-764. doi:10.1002/jmri.20319


Author Stadler, Alfred
Jakob, Peter M.
Griswold, Mark
Barth, Markus
Bankier, Alexander A.
Title T1 mapping of the entire lung parenchyma: influence of the respiratory phase in healthy individuals
Journal name Journal of Magnetic Resonance Imaging   Check publisher's open access policy
ISSN 1053-1807
1522-2586
Publication date 2005-06
Sub-type Article (original research)
DOI 10.1002/jmri.20319
Open Access Status Not yet assessed
Volume 21
Issue 6
Start page 759
End page 764
Total pages 6
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Language eng
Formatted abstract
Purpose: To determine the effect of respiratory phase on the T1 values of the entire lung.

Materials and Methods: We calculated T1 relaxation time on a pixel-by-pixel analysis of a series of Snapshot FLASH tomograms acquired after a single inversion pulse. Two sets of coronal T1 maps were acquired, one in full suspended inspiration and one in suspended expiration.

Results: The average of the mean T1 values over the entire lung in inspiration was 1199 ± 117 msec, the average of the mean T1 values in expiration was 1333 ± 167 msec. This difference was statistically significant, at P = 0.005. In inspiration the average coefficient of variation was 182 ± 56 msec, in expiration it was 153 ± 41 msec. This difference was not statistically significant.

Conclusion: T1 measurements of the entire lung are feasible. Our findings underline the need for a close monitoring of the inspirational status during MR examinations of the thorax, notably when T1 measurements of the lung are performed.
Keyword Lung
Monitoring
MRI
Respiratory phases
T1 map
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
 
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