Kontrastmittelanwendung auf Hochfeld-(3 T-)MRT

Trattnig, S., Ba-Ssalamah, A., Nobauer-Huhmann, I. M., Barth, M., Pinker, K. and Mlynarik, V. (2004) Kontrastmittelanwendung auf Hochfeld-(3 T-)MRT. Der Radiologe, 44 1: 56-64. doi:10.1007/s00117-003-0964-x

Author Trattnig, S.
Ba-Ssalamah, A.
Nobauer-Huhmann, I. M.
Barth, M.
Pinker, K.
Mlynarik, V.
Title Kontrastmittelanwendung auf Hochfeld-(3 T-)MRT
Translated title Use of contrast agent in high-field MRI (3T)
Language of Title ger
Journal name Der Radiologe   Check publisher's open access policy
Translated journal name Radiologe
Language of Journal Name ger
ISSN 0033-832X
Publication date 2004-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s00117-003-0964-x
Open Access Status Not yet assessed
Volume 44
Issue 1
Start page 56
End page 64
Total pages 9
Place of publication Heidelberg, Germany
Publisher Springer
Language ger
Abstract The basic diagnostic efficacy of MR contrast medium in the evaluation of primary brain tumors and its clinical usefulness in the detection of brain metastases with single and cumulative triple-dose was compared using a high-field 3T MR unit and a 1.5 T MR unit. Additionally, the effect of contrast agent on high-resolution MR venography based on the BOLD effect was evaluated at both field strengths. Tumor-brain contrast after gadodiamide administration, as assessed by means of statistical evaluation of MP-RAGE scans and T1-SE images, was significantly higher at 3 T than at 1.5 T. The subjective assessment of cumulative triple-dose 3 T images obtained the best results in the detection of brain metastases, followed by 1.5 T cumulative triple-dose enhanced images. Due to higher spatial resolution, contrast-enhanced MR venography at 3 T showed more details in and around tumors than at 1.5 T, additionally enhanced by stronger susceptibility weighting and higher signal-to-noise ratio at 3 T. In summary, administration of gadolinium-based contrast agent produces higher contrast between tumor and normal brain at 3 T than at 1.5 T, helps to detect more cerebral metastases at 3 T than at 1.5 T in single and cumulative triple dose, and improves MR venography at 3 T with increase in spatial resolution within the same measurement time, thus providing more detailed information.
Keyword 3 T MRI
Brain tumors
High field strength
MRI contrast agent
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Centre for Advanced Imaging Publications
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