Oral Cancer Massively Parallel Sequencing Data

Farah, Camile S. (2013): Oral Cancer Massively Parallel Sequencing Data. The University of Queensland. Collection.

Project name Oral Cancer Massively Parallel Sequencing Data
Project description
Next Generation Sequencing of Oral Cancer (Massively Parallel Sequencing Data)
Contact name Camile S. Farah
Contact email c.farah@uq.edu.au
Creator name Farah, Camile S.
Creator(s) role Head, Oral Oncology Research Program, UQCCR
Dataset name Oral Cancer Massively Parallel Sequencing Data
Dataset description
 1. Exome sequence data of oral squamous cell carcinomas from 44 young (< 45 yo) and old (≥ 45 yo) patients.

2. Exome sequence data of 50 samples from both pre-oral cancer patients that have progressed to cancer (progressive cohort) and pre-oral cancer patients that have not (> 5 years) progressed to oral cancer.

3. Transcriptome data from oral cancer and pre-cancer cell lines.

4. Transcriptome data from oral pre-cancer surgical margins.

5. Transcriptome data from oral cancer and precancerous lesions.

The significance of the data truly lies in the uniqueness of the collected sequenced samples over the last 50 years. Archival tissues, collected over the past 50 years both in the form of formalin fixed paraffin embedded and fresh frozen tissues, have allowed us to design experiments to answer questions regarding the genetic contribution to the development of oral cancer and the underlying genomic changes that dictate progression to oral cancer from a precursor lesion.

Data consists of Applied Biosystems 5500XL sequencing machine output files.
Access conditions Mediated Access
ANZSRC Field of Research (FoR) Code 110505 Oral Medicine and Pathology
060408 Genomics
111203 Cancer Genetics
Type of data Sequencing data
Binary files
Data Volume 60TB
Language eng
Collection start date 1964
Keyword Cancer genetics
Oral cancer
Cancer progression
Next generation sequencing
Collection type Collection
Publisher The University of Queensland
Publication Year 2013
Copyright notice 2013, The University of Queensland
Additional Notes https://services.qriscloud.org.au/access/f7dd6529281743959958045d1e8645f2/user

Document type: Data Collection
Collections: UQ Centre for Clinical Research Publications
Research Data Collections
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Created: Tue, 18 Mar 2014, 13:12:18 EST by Belinda Weaver