A Novel Platform Built on Designed Materials for Purification, Enrichment and Detection of Bio-Molecules

Qian, Kun (2013). A Novel Platform Built on Designed Materials for Purification, Enrichment and Detection of Bio-Molecules PhD Thesis, Australian Institute of Bioengineering and Nanotechnology, The University of Queensland.

       
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Author Qian, Kun
Thesis Title A Novel Platform Built on Designed Materials for Purification, Enrichment and Detection of Bio-Molecules
School, Centre or Institute Australian Institute of Bioengineering and Nanotechnology
Institution The University of Queensland
Publication date 2013
Thesis type PhD Thesis
Supervisor Chengzhong Yu
Michael Monteiro
Wenyi Gu
Total pages 189
Language eng
Subjects 090403 Chemical Engineering Design
100402 Medical Biotechnology Diagnostics (incl. Biosensors)
030302 Nanochemistry and Supramolecular Chemistry
Formatted abstract
In bio-medical and bio-analytical research, it is essential to track bio-molecules (e.g. proteins, peptides and other small molecules), which can be biomarkers of various biological process and may contain critical evidence for forensics. Addressing the analytical difficulties towards bio-molecules in real case bio-samples, this thesis presented a platform technology based on novel nano-materials/devices towards advanced mass spectrometry analysis, superior to conventional protocols and commercial products. The materials/devices were synthesized and engineered in a controlled manner for highly efficient purification, enrichment and detection of bio-molecules in diverse biological systems, showing huge application potential for personalized medicine and diagnostics.
Keyword Biotechnology
Engineering
Materials
Synthesis
Purification
Enrichment
Detection

 
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Created: Mon, 10 Mar 2014, 15:56:45 EST by Kun Qian on behalf of Scholarly Communication and Digitisation Service