There is a growing interest in the link between the developing brain and maximizing outcomes in schools. Recent research outcomes in many western countries indicate that students tend to fall behind on global scales in terms of ranking. Every three years since 2000 the Organization for Economic Co-Operation and Development have provided a report on the rankings of knowledge of 15 year-olds. The 5th report – the 2012 Programme for International Student Assessment report (PISA) was released late 2013 (OECD 2013). This report is based on the results 510 000 students from 65 countries between the ages of 15 years 3 months and 16 years 2 months of age representing 28 million 15-year old students globally and 80% of the world economy. Demographic information was collected through questions to students and their school principals regarding the student’s background, the school, the learning environment and school systems.