Reproducibility of anterior chamber angle measurement using the tongren ultrasound biomicroscopy analysis system

Lin, Zhong, Mou, Da P., Liang, Yuan B., Li, Si Z., Zhang, Rui, Fan, Su J., Wang, Ning L. and Thomas, Ravi (2014) Reproducibility of anterior chamber angle measurement using the tongren ultrasound biomicroscopy analysis system. Journal of Glaucoma, 23 2: 61-68. doi:10.1097/IJG.0b013e3182698094


Author Lin, Zhong
Mou, Da P.
Liang, Yuan B.
Li, Si Z.
Zhang, Rui
Fan, Su J.
Wang, Ning L.
Thomas, Ravi
Title Reproducibility of anterior chamber angle measurement using the tongren ultrasound biomicroscopy analysis system
Journal name Journal of Glaucoma   Check publisher's open access policy
ISSN 1057-0829
1536-481X
Publication date 2014-02
Year available 2014
Sub-type Article (original research)
DOI 10.1097/IJG.0b013e3182698094
Open Access Status
Volume 23
Issue 2
Start page 61
End page 68
Total pages 8
Place of publication Philadelphia, United States
Publisher Lippincott Williams & Wilkins
Collection year 2015
Language eng
Subject 2731 Ophthalmology
Formatted abstract
PURPOSE: To assess the intraobserver and interobserver variability of new software for the analysis of anterior chamber-angle images obtained using ultrasound biomicroscopy (UBM).

PATIENTS AND METHODS: Consecutive UBM images of 4 quadrants (the superior, the nasal, the temporal, and the inferior) of 30 primary angle-closure suspects (PACSs) and 30 normal subjects with open angles were selected. Two observers used the new UBM image analysis software to calculate the following parameters on 2 separate occasions: angle opening distance (AOD), trabecular-iris angle (TIA), angle recess area (ARA), trabecular-ciliary process distance (TCPD), iris-ciliary process distance (ICPD), and iris thickness (IT). Intraobserver and interobserver reproducibility were measured using intraclass correlation coefficient (ICC) and Bland-Altman plots.

RESULTS: For intraobserver measurements in PACS, the range of ICC for AODs, TIAs, ARAs, TCPDs, ICPDs, and ITs in the 4 quadrants were 0.77 to 0.94, 0.80 to 0.92, 0.82 to 0.94, 0.51 to 0.73, 0.42 to 0.78, and 0.76 to 0.89; in open angles, these were 0.83 to 0.94, 0.80 to 0.93, 0.84 to 0.93, 0.57 to 0.89, 0.57 to 0.84, and 0.70 to 0.95. For interobserver measurements in PACS, the range of ICC for AODs, TIAs, ARAs, TCPDs, ICPDs, and ITs in the same quadrants as above were 0.52 to 0.89, 0.65 to 0.92, 0.68 to 0.92, 0.22 to 0.80, 0.48 to 0.93, and 0.29 to 0.75; in open angles, these were 0.57 to 0.87, 0.60 to 0.86, 0.64 to 0.90, 0.27 to 0.94, 0.56 to 0.93, and 0.28 to 0.66.

CONCLUSIONS: Angle width (AOD, TIA, and ARA) and IT of both PACS and open angles could be reliably measured by the same observer; interobserver measurements and those related to the ciliary process (TCPD and ICPD) were more variable. For the current version of this software, we recommend measurements of anterior chamber parameters by the same observer.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Medicine Publications
 
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