Absence of an important vaccine and diagnostic target in carriageand disease-related nontypeable Haemophilus influenzae

Smith-Vaughan, Heidi C., Chang, Anne B., Sarovich, Derek S., Marsh, Robyn L., Grimwood, Keith, Leach, Amanda J., Morris, Peter S. and Price, Erin P. (2014) Absence of an important vaccine and diagnostic target in carriageand disease-related nontypeable Haemophilus influenzae. Clinical and Vaccine Immunology, 21 2: 250-252. doi:10.1128/CVI.00632-13


Author Smith-Vaughan, Heidi C.
Chang, Anne B.
Sarovich, Derek S.
Marsh, Robyn L.
Grimwood, Keith
Leach, Amanda J.
Morris, Peter S.
Price, Erin P.
Title Absence of an important vaccine and diagnostic target in carriageand disease-related nontypeable Haemophilus influenzae
Formatted title
Absence of an important vaccine and diagnostic target in carriageand disease-related nontypeable Haemophilus influenzae 
Journal name Clinical and Vaccine Immunology   Check publisher's open access policy
ISSN 1556-6811
1556-679X
Publication date 2014
Year available 2013
Sub-type Article (original research)
DOI 10.1128/CVI.00632-13
Open Access Status DOI
Volume 21
Issue 2
Start page 250
End page 252
Total pages 3
Place of publication Washington, DC, United States
Publisher American Society for Microbiology
Collection year 2014
Language eng
Formatted abstract
Nontypeable Haemophilus influenzae (NTHi)-associated disease is a major health problem globally. Whole-genome sequence analysis identified the absence of hpd genes encoding Haemophilus protein D in 3 of 16 phylogenetically distinct NTHi isolates. This novel finding is of potential clinical significance, as protein D and hpd represent important NTHi vaccine antigen and diagnostic targets, respectively.  
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

 
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