Reallocating time to sleep, sedentary behaviors, or active behaviors: Associations with cardiovascular disease risk biomarkers, NHANES 2005-2006

Buman, Matthew P., Winkler, Elisabeth A. H., Kurka, Jonathan M., Hekler, Eric B., Baldwin, Carol M., Owen, Neville, Ainsworth, Barbara E., Healy, Genevieve N. and Gardiner, Paul A. (2014) Reallocating time to sleep, sedentary behaviors, or active behaviors: Associations with cardiovascular disease risk biomarkers, NHANES 2005-2006. American Journal of Epidemiology, 179 3: 323-334. doi:10.1093/aje/kwt292


Author Buman, Matthew P.
Winkler, Elisabeth A. H.
Kurka, Jonathan M.
Hekler, Eric B.
Baldwin, Carol M.
Owen, Neville
Ainsworth, Barbara E.
Healy, Genevieve N.
Gardiner, Paul A.
Title Reallocating time to sleep, sedentary behaviors, or active behaviors: Associations with cardiovascular disease risk biomarkers, NHANES 2005-2006
Journal name American Journal of Epidemiology   Check publisher's open access policy
ISSN 0002-9262
1476-6256
Publication date 2014-02
Year available 2013
Sub-type Article (original research)
DOI 10.1093/aje/kwt292
Open Access Status
Volume 179
Issue 3
Start page 323
End page 334
Total pages 12
Place of publication Cary, NC, United States
Publisher Oxford University Press
Collection year 2014
Language eng
Abstract Sleep and sedentary and active behaviors are linked to cardiovascular disease risk biomarkers, and across a 24-hour day, increasing time in 1 behavior requires decreasing time in another. We explored associations of reallocating time to sleep, sedentary behavior, or active behaviors with biomarkers. Data (n = 2,185 full sample; n = 923 fasting subanalyses) from the cross-sectional 2005-2006 US National Health and Nutrition Examination Survey were analyzed. The amounts of time spent in sedentary behavior, light-intensity activity, and moderate-to-vigorous physical activity (MVPA) were derived from ActiGraph accelerometry (ActiGraph LLC, Pensacola, Florida), and respondents reported their sleep duration. Isotemporal substitution modeling indicated that, independent of potential confounders and time spent in other activities, beneficial associations (P < 0.05) with cardiovascular disease risk biomarkers were associated with the reallocation of 30 minutes/day of sedentary time with equal time of either sleep (2.2% lower insulin and 2.0% lower homeostasis model assessment of β-cell function), light-intensity activity (1.9% lower triglycerides, 2.4% lower insulin, and 2.2% lower homeostasis model assessment of β-cell function), or MVPA (2.4% smaller waist circumference, 4.4% higher high-density lipoprotein cholesterol, 8.5% lower triglycerides, 1.7% lower glucose, 10.7% lower insulin, and 9.7% higher homeostasis model assessment of insulin sensitivity. These findings provide evidence that MVPA may be the most potent health-enhancing, time-dependent behavior, with additional benefit conferred from light-intensity activities and sleep duration when reallocated from sedentary time.
Keyword Cardiovascular disease
Isotemporal substitution
Physical activity
Sedentary behavior
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online 6 December 2013

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Public Health Publications
 
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