The role of candidal histolytic enzymes on denture-induced stomatitis in patients living in retirement homes

de Menezes Thiele, Magna Carvalho, de Paula e Carvalho, Alessandra, Gursky, Lauren Christine, Rosa, Rosimeire Takaki, Samaranayake, Lakshman Perera and Ribeiro Rosa, Edvaldo Antonio (2008) The role of candidal histolytic enzymes on denture-induced stomatitis in patients living in retirement homes. Gerodontology, 25 4: 229-236. doi:10.1111/j.1741-2358.2008.00221.x


Author de Menezes Thiele, Magna Carvalho
de Paula e Carvalho, Alessandra
Gursky, Lauren Christine
Rosa, Rosimeire Takaki
Samaranayake, Lakshman Perera
Ribeiro Rosa, Edvaldo Antonio
Title The role of candidal histolytic enzymes on denture-induced stomatitis in patients living in retirement homes
Journal name Gerodontology   Check publisher's open access policy
ISSN 0734-0664
1741-2358
Publication date 2008
Sub-type Article (original research)
DOI 10.1111/j.1741-2358.2008.00221.x
Open Access Status
Volume 25
Issue 4
Start page 229
End page 236
Total pages 8
Place of publication Malden, MA, United States
Publisher Wiley-Blackwell
Language eng
Abstract Material and methods: Fifty nine elders wearing complete dentures and living in retirement homes in Curitiba (southern Brazil), were divided into two groups: group #1, 26 patients with denture-induced stomatitis and group #2, 33 patients without denture-induced stomatitis. The two groups were evaluated in relation to the degree of denture-induced stomatitis, salivary fungal loads, and secretion of some histolytic enzymes. Results: Patients from group #1 showed higher degrees of colonisation by Candida albicans (p = 0.031). Candida krusei, Candida tropicalis, and Candida parapsilosis were also isolated, but there were no differences between the groups (p > 0.05). Secretory aspartyl protease (Sap) and chondroitinase did not show significant differences among the isolated Candida spp. in the two groups. Phospholipase secretion rates were higher among the strains of C. albicans from group #2 (p = 0.036). The same behaviour was not detected for non-albicans Candida species. Conclusions: The results could infer that differences in the secretion rates of candidal histolytic enzymes should not be imputed as imperative for the progress of denture-induced stomatitis.
Keyword Chondroitinase
Denture-induced stomatitis
Phospholipase
Secretory aspartyl protease
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Dentistry Publications
 
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