Clindamycin in dentistry: more than just effective prophylaxis for endocarditis?

Brook, Itzhak, Lewis, Mike A. O., Sandor, George K. B., Jeffcoat, Marjorie, Samaranayake, L. P. and Rojas, Jorge Vera (2005) Clindamycin in dentistry: more than just effective prophylaxis for endocarditis?. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, 100 5: 550-558. doi:10.1016/j.tripleo.2005.02.086


Author Brook, Itzhak
Lewis, Mike A. O.
Sandor, George K. B.
Jeffcoat, Marjorie
Samaranayake, L. P.
Rojas, Jorge Vera
Title Clindamycin in dentistry: more than just effective prophylaxis for endocarditis?
Journal name Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology   Check publisher's open access policy
ISSN 1079-2104
2212-4411
Publication date 2005-11
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.tripleo.2005.02.086
Open Access Status Not yet assessed
Volume 100
Issue 5
Start page 550
End page 558
Total pages 9
Place of publication Amsterdam, Netherlands
Publisher Elsevier BV
Language eng
Abstract Clindamycin is a broad-spectrum antibiotic with activity against aerobic, anaerobic, and β-lactamase-producing pathogens. This antibiotic has been used for many years as prophylactic treatment during dental procedures to prevent endocarditis. However, the spectrum and susceptibility of the bacteria species involved in dental infections indicate that clindamycin would also be an effective treatment option for these conditions. In addition to its antiinfective properties, clindamycin has high oral absorption, significant tissue penetration, including penetration into bone, and stimulatory effects on the host immune system. This review discusses the microbiologic and clinical evidence supporting the efficacy and safety of clindamycin for the successful management of dental infections.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: School of Dentistry Publications
MVM records
 
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Citation counts: TR Web of Science Citation Count  Cited 24 times in Thomson Reuters Web of Science Article | Citations
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