Classification of retinal ganglion cells in the southern hemisphere lamprey Geotria australis (Cyclostomata)

Fletcher, Lee Norman, Coimbra, Joao Paulo, Rodger, Jennifer, Potter, Ian C., Gill, Howard S., Dunlop, Sarah A. and Collin, Shaun P. (2014) Classification of retinal ganglion cells in the southern hemisphere lamprey Geotria australis (Cyclostomata). Journal of Comparative Neurology, 522 4: 750-771. doi:10.1002/cne.23441


Author Fletcher, Lee Norman
Coimbra, Joao Paulo
Rodger, Jennifer
Potter, Ian C.
Gill, Howard S.
Dunlop, Sarah A.
Collin, Shaun P.
Title Classification of retinal ganglion cells in the southern hemisphere lamprey Geotria australis (Cyclostomata)
Formatted title
Classification of retinal ganglion cells in the southern hemisphere lamprey Geotria australis (Cyclostomata)
Journal name Journal of Comparative Neurology   Check publisher's open access policy
ISSN 0021-9967
1096-9861
Publication date 2014-03
Year available 2014
Sub-type Article (original research)
DOI 10.1002/cne.23441
Open Access Status
Volume 522
Issue 4
Start page 750
End page 771
Total pages 22
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Collection year 2015
Language eng
Formatted abstract
Lampreys are one of two extant representatives of the earliest group of vertebrates, the agnathans or jawless fishes. The single species of the southern hemisphere lamprey family Geotriidae, Geotria australis, possesses the potential for pentachromatic color discrimination opposed to the mono- or dichromacy found in other lampreys. However, little is known of the retinal ganglion cell types that contribute to visual processing in G. australis. A quantitative morphological approach was used to distinguish and describe retinal ganglion cell types in G. australis. The morphology of retinal ganglion cells was revealed by retrograde biocytin labeling from the optic disc. Cells were digitally reconstructed, and somatic area and position and dendritic field size, density, tortuosity, and stratification were subjected to quantitative morphometric analyses. Cluster analysis, in conjunction with similarity profile analysis (SIMPROF), statistically identified five discrete monostratified retinal ganglion cell types, one of which may comprise two subtypes. Two bistratified types were identified separately, including a biplexiform and a bistratified subtype. The use of cluster analysis with SIMPROF provided a robust statistical technique for objectively identifying cell types whose characteristics were similar and significantly different from those of other types and thus provides an objective resolution of the problems posed by "lumpers vs. splitters" when designating cell types. The diversity of retinal ganglion cells suggests that visual information in the lamprey G. australis is processed in parallel streams, as in gnathostomes. These findings, together with the results of previous studies, indicate that the visual system of the lamprey G. australis represents the upper limit of visual complexity in extant agnathans.
Keyword Vision
Retina
Morphology
Evolution
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2015 Collection
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 2 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 09 Feb 2014, 00:05:35 EST by System User on behalf of Queensland Brain Institute