Maternal depressive, anxious, and stress symptoms during pregnancy predict internalizing problems in adolescence

Betts, Kim S., Williams, Gail M., Najman, Jacob M. and Alati, Rosa (2014) Maternal depressive, anxious, and stress symptoms during pregnancy predict internalizing problems in adolescence. Depression and Anxiety, 31 1: 9-18. doi:10.1002/da.22210


Author Betts, Kim S.
Williams, Gail M.
Najman, Jacob M.
Alati, Rosa
Title Maternal depressive, anxious, and stress symptoms during pregnancy predict internalizing problems in adolescence
Journal name Depression and Anxiety   Check publisher's open access policy
ISSN 1091-4269
1520-6394
Publication date 2014
Year available 2013
Sub-type Article (original research)
DOI 10.1002/da.22210
Open Access Status
Volume 31
Issue 1
Start page 9
End page 18
Total pages 10
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Collection year 2014
Language eng
Formatted abstract
Background: Studies have shown a link between maternal-prenatal mental health and offspring behavior problems. In this paper, we derived longitudinal trajectories of maternal depressive, anxious, and stress symptoms over early life to predict offspring behavior in adolescence.

Methods: Participants included 3,925 mother-offspring pairs from the Mater University Study of Pregnancy (MUSP), an Australian-based, prebirth cohort study. Latent class growth analysis with parallel processes was used to identify trajectories of maternal depressive, anxious, and stress symptoms over four measurement periods between the mothers' first clinic visit and 5 years postpregnancy. The estimates from the maternal trajectories were used to fit multivariate logistic regression models and predict internalizing and externalizing behavior at age 14. We adjusted for a wide range of factors, including a number of prenatal confounders, concurrent maternal depressive and anxious symptoms, father's history of mental problems, and maternal life events relationship quality and contact with the new born.

Results: Seven maternal trajectories were identified one of which isolated high levels of depressive, anxious, and stress symptoms during pregnancy. After adjustment for confounders, this was the only trajectory that predicted higher internalizing behavior in adolescence. No specific maternal trajectory predicted externalizing problems.

Conclusions: We found evidence for a prenatal effect, whereby high levels of maternal depression, anxiety, and stress symptoms in early pregnancy uniquely increased the risk of internalizing behavior problems in adolescence. 
Keyword Adolescence
Anxiety and stress
Externalizing
Internalizing
Latent class growth analysis
Prenatal depression
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Citation counts: TR Web of Science Citation Count  Cited 9 times in Thomson Reuters Web of Science Article | Citations
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