Understanding the diffusion of dextrans in 'Click' PNIPAAm hydrogels

Ooi, Huey Wen, Peng, Hui, Jack, Kevin S. and Whittaker, Andrew K. (2014) Understanding the diffusion of dextrans in 'Click' PNIPAAm hydrogels. Australian Journal of Chemistry, 67 1: 85-92. doi:10.1071/CH13333

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Author Ooi, Huey Wen
Peng, Hui
Jack, Kevin S.
Whittaker, Andrew K.
Title Understanding the diffusion of dextrans in 'Click' PNIPAAm hydrogels
Journal name Australian Journal of Chemistry   Check publisher's open access policy
ISSN 0004-9425
Publication date 2014
Year available 2013
Sub-type Article (original research)
DOI 10.1071/CH13333
Volume 67
Issue 1
Start page 85
End page 92
Total pages 8
Place of publication Collingwood, VIC Australia
Publisher C S I R O Publishing
Collection year 2014
Language eng
Subject 1600 Chemistry
Abstract Arguably the most important property of a hydrogel is the ability to allow the diffusion of solutes through the crosslinked network. Studies of the diffusion in hydrogels are important for providing information on the rate and extent of the passage of the solute and on the details of the microstructure of the hydrogel. Such knowledge is directly relevant for applications such as controlled drug delivery systems. The structure of novel poly(N- isopropylacrylamide) (PNIPAAm) hydrogels can be revealed by the restricted diffusion of appropriate probe molecules. Dextran molecules, labelled with fluorescent moieties, were incorporated into well-defined PNIPAAm hydrogels to investigate the effects of hydrogel mesh size and dextran molecular size on the diffusivities of solute molecules.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

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