Quantification of tissue shrinkage in canine intestinal specimens after resection and fixation

Clarke, Ben S., Banks, Tania A. and Findji, Laurent (2014) Quantification of tissue shrinkage in canine intestinal specimens after resection and fixation. Canadian Journal of Veterinary Research, 78 1: 46-49.

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Author Clarke, Ben S.
Banks, Tania A.
Findji, Laurent
Title Quantification of tissue shrinkage in canine intestinal specimens after resection and fixation
Journal name Canadian Journal of Veterinary Research   Check publisher's open access policy
ISSN 0830-9000
1928-9022
Publication date 2014-01
Year available 2014
Sub-type Article (original research)
Volume 78
Issue 1
Start page 46
End page 49
Total pages 4
Place of publication Ottawa, Canada
Publisher Canadian Veterinary Medical Association
Collection year 2015
Language eng
Abstract The aim of this study was to quantify the longitudinal shrinkage of canine small intestinal specimens after resection and fixation in 10% formalin. Samples were obtained from 12 clinically normal dogs of medium to large breed via ventral midline coeliotomy and enterectomy. The length of each sample was measured before excision, immediately after excision, and after 24 h in 10% formalin. The results were interpreted with the use of single-sample t-tests of the average changes; P-values of less than 0.01 were considered significant. The samples indicated a significant decrease in length after resection and fixation. The mean shrinkage from the pre-excision state was 28.3% immediately after excision (P < 0.0001) and 26.3% after 24 h of fixation (P < 0.0001). There was a small but not significant increase in the length of the specimens between the 2nd and 3rd measurement points. Quantification of the longitudinal shrinkage of resected intestinal specimens may improve interpretation of the distance of surgical margins from abnormal tissue in histopathology reports and allow investigation of the margins required for the clearance of specific tumors.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2015 Collection
School of Veterinary Science Publications
 
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Created: Thu, 16 Jan 2014, 13:48:47 EST by Dr Tania Banks on behalf of School of Veterinary Science