To cap or not to cap: chemotherapy dosing in obese adult haematology patients

Sanduh, G., Mapp, S., Carrington, C. and Hennig, S. (2014) To cap or not to cap: chemotherapy dosing in obese adult haematology patients. Clinical Pharmacology and Therapeutics, 95 4: 356-358. doi:10.1038/clpt.2014.3

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Author Sanduh, G.
Mapp, S.
Carrington, C.
Hennig, S.
Title To cap or not to cap: chemotherapy dosing in obese adult haematology patients
Journal name Clinical Pharmacology and Therapeutics   Check publisher's open access policy
ISSN 0009-9236
1532-6535
1085-8733
Publication date 2014-04
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1038/clpt.2014.3
Open Access Status
Volume 95
Issue 4
Start page 356
End page 358
Total pages 3
Place of publication New York, NY, United States
Publisher Nature Publishing Group
Collection year 2015
Language eng
Formatted abstract
Obesity, defined by the World Health Organization (WHO) as a body mass index (BMI) of ≥30 kg/m2, is a risk factor for many cancers and may be associated with higher cancer-related mortality.1 In comparison to solid tumors, the influence of obesity on the prevalence, pathophysiology, treatment, and disease outcomes of hematological cancers such as lymphoma, leukemia, and plasma cell disorders is less well defined. As the incidence of obesity increases (according to WHO projections, by 2015 more than 700 million adults worldwide will be obese), clinicians treating blood cancers are increasingly aware of the uncertainties and disparities with drug treatment within this group, especially in determining the most appropriate chemotherapy dosing algorithms that take into account the changes in anticancer drug pharmacokinetics and pharmacodynamics to optimize outcomes.
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Non HERDC
School of Pharmacy Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 2 times in Scopus Article | Citations
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Created: Wed, 15 Jan 2014, 13:53:33 EST by Dr Stefanie Hennig on behalf of School of Pharmacy