Ectodermal dysplasia: skinny models on the catwalk

Duijf, Pascal H. G. and van Bokhoven, Hans (2005) Ectodermal dysplasia: skinny models on the catwalk. Drug Discovery Today: Disease Models, 2 2: 111-118. doi:10.1016/j.ddmod.2005.05.006

Author Duijf, Pascal H. G.
van Bokhoven, Hans
Title Ectodermal dysplasia: skinny models on the catwalk
Journal name Drug Discovery Today: Disease Models   Check publisher's open access policy
ISSN 1740-6757
Publication date 2005
Sub-type Article (original research)
DOI 10.1016/j.ddmod.2005.05.006
Volume 2
Issue 2
Start page 111
End page 118
Total pages 8
Editor Per Lindahl
Place of publication London, United Kingdom
Publisher Trends Journals, Elsevier
Language eng
Formatted abstract
Ectodermal dysplasia (ED) is characterized by aberrant development of the hair, nails, teeth and/or sweat glands. Genetic defects are the primary cause of ED and involve genes encoding proteins implicated in EDA-NF-κB signaling, desmosome stabilization and transcription factors, among others. This review discusses the pros and cons of in vitro and in vivo models that are used in research today aimed at understanding the pathogenesis of ED and underlying genetic defects.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Diamantina Institute - Open Access Collection
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Created: Thu, 05 Dec 2013, 15:38:19 EST by Pascal Duijf on behalf of UQ Diamantina Institute