Development of an anti-CDCP1 ELISA

Lau, Kevin (2013). Development of an anti-CDCP1 ELISA MPhil Thesis, School of Medicine, The University of Queensland.

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Author Lau, Kevin
Thesis Title Development of an anti-CDCP1 ELISA
School, Centre or Institute School of Medicine
Institution The University of Queensland
Publication date 2013
Thesis type MPhil Thesis
Supervisor Jon Cohen
John Hooper
Total pages 82
Language eng
Subjects 110323 Surgery
Formatted abstract
CDCP1is a transmembrane glycoprotein shown to be responsible for invasion and metastasis of cancer cells in vitro. Using the ELISA (Enzyme-Linked ImmunoSorbent Assay) technique, we measured CDCP1levels reliably among human serum samples.

CDCP1 levels were positively detected in 8 of 36 cancer group patients (22%), compared to 5 of 32 (15%) control group patients . Our results showed that it is possible to use the developed ELISA to measure CDCP1 levels in human serum. However, with our limited sample size, we could not reliably make any conclusions yet of any strong associations between colorectal cancer and CDCP1 levels.
Keyword CUB domain containing protein 1
Colorectal cancer
Colon cancer
Western blotting

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Created: Thu, 05 Dec 2013, 03:35:41 EST by Dr Kevin Lau on behalf of Scholarly Communication and Digitisation Service