Environmental risk factors for schizophrenia

McGrath, John J. and Murray, Robin M. (2011). Environmental risk factors for schizophrenia. In Daniel R. Weinberger and Paul J. Harrison (Ed.), Schizophrenia 3rd ed. (pp. 226-244) Chichester, West Sussex, UK: Blackwell Publishing. doi:10.1002/9781444327298.ch11

Author McGrath, John J.
Murray, Robin M.
Title of chapter Environmental risk factors for schizophrenia
Title of book Schizophrenia
Place of Publication Chichester, West Sussex, UK
Publisher Blackwell Publishing
Publication Year 2011
Sub-type Research book chapter (original research)
DOI 10.1002/9781444327298.ch11
Open Access Status
Edition 3rd
ISBN 9781405176972
Editor Daniel R. Weinberger
Paul J. Harrison
Chapter number 11
Start page 226
End page 244
Total pages 19
Total chapters 33
Language eng
Subjects 2700 Medicine
Formatted Abstract/Summary
Data have steadily accumulated that link various environmental exposures with an increased risk of schizophrenia. This chapter summarizes the evidence for various prenatal exposures, including candidates related to infection, nutrition, and pregnancy and birth complications. Migrant status and growing up in urban settings have also been linked to an increased risk of schizophrenia, thus suggesting a role for stress-related mechanisms in the etiology of schizophrenia. Recent evidence has found an association between advanced paternal age and an increased risk of schizophrenia. Finally, the contribution of illicit drugs such as cannabis to an increased risk of schizophrenia is detailed. This chapter provides a concise summary of this evidence, and outlines general directions for future research.
Keyword Cannabis
Paternal age
Pregnancy and birth complications
Prenatal infection
Prenatal nutrition
Risk factor
Social biology
Q-Index Code B1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Book Chapter
Collection: Queensland Brain Institute Publications
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