Perioperative medication management: Expanding the role of the preadmission clinic pharmacist in a single centre, randomised controlled trial of collaborative prescribing

Hale, A. R., Coombes, I. D., Stokes, J., McDougall, D., Whitfield, K., Maycock, E. and Nissen, L. (2013) Perioperative medication management: Expanding the role of the preadmission clinic pharmacist in a single centre, randomised controlled trial of collaborative prescribing. BMJ Open, 3 7: . doi:10.1136/bmjopen-2013-003027


Author Hale, A. R.
Coombes, I. D.
Stokes, J.
McDougall, D.
Whitfield, K.
Maycock, E.
Nissen, L.
Title Perioperative medication management: Expanding the role of the preadmission clinic pharmacist in a single centre, randomised controlled trial of collaborative prescribing
Journal name BMJ Open   Check publisher's open access policy
ISSN 2044-6055
Publication date 2013-01-01
Year available 2013
Sub-type Article (original research)
DOI 10.1136/bmjopen-2013-003027
Open Access Status DOI
Volume 3
Issue 7
Total pages 11
Place of publication London, United Kingdom
Publisher B M J Group
Collection year 2014
Language eng
Subject 2700 Medicine
Abstract Objectives: Current evidence to support non-medical prescribing is predominantly qualitative, with little evaluation of accuracy, safety and appropriateness. Our aim was to evaluate a new model of service for the Australia healthcare system, of inpatient medication prescribing by a pharmacist in an elective surgery preadmission clinic (PAC) against usual care, using an endorsed performance framework. Design: Single centre, randomised controlled, two-arm trial. Setting: Elective surgery PAC in a Brisbane-based tertiary hospital. Participants: 400 adults scheduled for elective surgery were randomised to intervention or control. Intervention: A pharmacist generated the inpatient medication chart to reflect the patient's regular medication, made a plan for medication perioperatively and prescribed venous thromboembolism (VTE) prophylaxis. In the control arm, the medication chart was generated by the Resident Medical Officers. Outcome measures: Primary outcome was frequency of omissions and prescribing errors when compared against the medication history. The clinical significance of omissions was also analysed. Secondary outcome was appropriateness of VTE prophylaxis prescribing. Results: There were significantly less unintended omissions of medications: 11 of 887 (1.2%) intervention orders compared with 383 of 1217 (31.5%) control (p<0.001). There were significantly less prescribing errors involving selection of drug, dose or frequency: 2 in 857 (0.2%) intervention orders compared with 51 in 807 (6.3%) control (p<0.001). Orders with at least one component of the prescription missing, incorrect or unclear occurred in 208 of 904 (23%) intervention orders and 445 of 1034 (43%) controls (p<0.001). VTE prophylaxis on admission to the ward was appropriate in 93% of intervention patients and 90% controls (p=0.29). Conclusions: Medication charts in the intervention arm contained fewer clinically significant omissions,.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Pharmacy Publications
 
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